Butternut Squash & Sausage Casserole

Featured in: Lazy Day Meals

This comforting bake brings together sweet roasted butternut squash, savory Italian sausage, and fluffy quinoa in one bubbling dish. The squash caramelizes beautifully alongside aromatic onions, garlic, and herbs while the sausage adds rich depth. Baby spinach brings freshness and color, then everything gets topped with mozzarella and Parmesan for that irresistible golden, cheesy crust. Ready in just over an hour, this gluten-free dinner serves six and fills your kitchen with incredible aromas. Perfect for meal prep too—assemble ahead and bake when ready.

Updated on Sun, 08 Feb 2026 00:34:08 GMT
Golden brown Cozy Butternut Squash & Sausage Casserole with melted mozzarella and fresh parsley garnish. Save to Pinterest
Golden brown Cozy Butternut Squash & Sausage Casserole with melted mozzarella and fresh parsley garnish. | snackandmack.com

When the crisp air of autumn settles in, there is nothing more satisfying than a warm, oven-baked meal. This Cozy Butternut Squash & Sausage Casserole brings together the earthy sweetness of roasted squash, savory Italian sausage, and nutrient-dense quinoa for a dish that is as nourishing as it is delicious. Topped with a layer of bubbly, melted cheese, it is the perfect centerpiece for a family dinner on a chilly evening.

Golden brown Cozy Butternut Squash & Sausage Casserole with melted mozzarella and fresh parsley garnish. Save to Pinterest
Golden brown Cozy Butternut Squash & Sausage Casserole with melted mozzarella and fresh parsley garnish. | snackandmack.com

The beauty of this casserole lies in its depth of flavor. By sautéing the aromatics and browning the sausage before baking, you create a savory base that perfectly complements the natural sugars of the butternut squash. The addition of thyme, sage, and paprika adds a warm, herbaceous profile that makes every bite feel like a celebration of the season.

Ingredients

  • Vegetables: 1 medium butternut squash (peeled, seeded, and cut into 1-inch cubes), 1 medium onion (diced), 2 cloves garlic (minced), 3 cups baby spinach, fresh parsley (optional garnish).
  • Meats & Protein: 1 pound Italian sausage (sweet or spicy, casing removed), 1 cup cooked quinoa.
  • Dairy: 1 cup shredded mozzarella cheese, ½ cup grated Parmesan cheese.
  • Pantry & Spices: 2 tablespoons olive oil, 1 teaspoon dried thyme, 1 teaspoon dried sage, 1 teaspoon paprika, salt and pepper to taste.
  • Liquids: 1 cup chicken or vegetable broth.
Product image
Grill meats and vegetables indoors with beautiful sear marks and easy cleanup using minimal oil.
Check price on Amazon

Instructions

1. Preheat and Prep
Preheat your oven to 375°F (190°C). Lightly grease a 9x13-inch baking dish with cooking spray or olive oil.
2. Sauté Aromatics
In a large skillet, heat olive oil over medium heat. Add the diced onion and cook until translucent, about 5 minutes. Stir in minced garlic and cook for 1 minute until fragrant.
3. Brown the Sausage
Increase the heat slightly, add the Italian sausage, and cook until browned and cooked through, breaking it apart with a wooden spoon for about 7–10 minutes.
4. Cook Squash and Season
Add the butternut squash to the skillet. Stir in dried thyme, dried sage, paprika, salt, and pepper. Cook for 5–7 minutes, stirring occasionally, until the squash starts to soften.
5. Combine Greens and Grains
Add the baby spinach and cooked quinoa, stirring until the spinach wilts.
6. Simmer
Pour in the chicken or vegetable broth and simmer for 3–4 minutes.
7. Assemble
Transfer the mixture to the prepared baking dish. Spread evenly and top with shredded mozzarella and grated Parmesan cheese.
8. Bake
Cover with aluminum foil and bake in the preheated oven for 25 minutes. Remove the foil and bake for an additional 15–20 minutes, or until the cheese is bubbly and golden brown.
9. Final Touch
Remove from the oven and let cool for 5 minutes. Garnish with fresh parsley before serving.

Zusatztipps für die Zubereitung

To make the preparation even easier, ensure you have a sharp chef's knife and a sturdy cutting board for the squash. This dish is also an excellent candidate for meal prep; you can assemble the entire casserole up to 2 days in advance and keep it refrigerated. If baking directly from the fridge, simply add a few extra minutes to the oven time.

Varianten und Anpassungen

Feel free to get creative with the ingredients! You can substitute the quinoa with cooked rice or couscous for a different texture. For a vegetarian version, swap the Italian sausage for plant-based sausage crumbles or a variety of hearty beans. You can also toss in other seasonal vegetables you have on hand, such as kale or mushrooms.

Serviervorschläge

Serve this casserole warm, garnished generously with fresh parsley. It pairs beautifully with a light red wine such as Pinot Noir, which complements the savory herbs, or a crisp white like Sauvignon Blanc for a refreshing contrast. A side of crusty bread or a simple green salad makes this a complete and elegant meal.

A scoop of Cozy Butternut Squash & Sausage Casserole revealing layers of sausage and quinoa. Save to Pinterest
A scoop of Cozy Butternut Squash & Sausage Casserole revealing layers of sausage and quinoa. | snackandmack.com

With its vibrant colors and rich, comforting flavors, this Cozy Butternut Squash & Sausage Casserole is bound to become a recurring favorite in your kitchen. It's a testament to how simple ingredients, when combined with care, can create a truly memorable meal.

Product image
Boil water quickly for tea, coffee, instant soups, and faster prep when cooking grains or noodles.
Check price on Amazon

Recipe FAQs

Can I make this casserole ahead of time?

Yes, assemble the entire dish up to 2 days before baking. Cover tightly and refrigerate. Add about 5-10 extra minutes to the baking time if baking cold from the refrigerator.

What can I substitute for the quinoa?

Cooked rice, couscous, or even farro work beautifully as grain alternatives. Each brings slightly different texture while maintaining the hearty, satisfying nature of the dish.

How do I make this vegetarian?

Replace the Italian sausage with plant-based sausage crumbles or add cannellini beans for protein. Use vegetable broth instead of chicken broth. The cooking times remain the same.

Can I freeze leftovers?

Absolutely. Portion cooled leftovers into airtight containers and freeze for up to 3 months. Thaw overnight in the refrigerator, then reheat in a 350°F oven until warmed through.

What wine pairs well with this casserole?

A light red like Pinot Noir complements the sausage and squash beautifully. For white wine lovers, a crisp Sauvignon Blanc cuts through the richness while balancing the sweet vegetables.

How do I know when the squash is fully cooked?

The squash should be tender when pierced with a fork but not mushy. It typically takes 5-7 minutes in the skillet plus the full baking time to reach perfect tenderness.

Butternut Squash & Sausage Casserole

A hearty baked dish combining roasted squash, savory sausage, quinoa, and bubbly cheese—perfect for chilly evenings.

Prep Time
20 min
Cook Time
50 min
Overall Time
70 min
Recipe by Snack And Mack Ryan Mitchell

Recipe Type Lazy Day Meals

Skill Level Easy

Cuisine Type American

Output 6 Serving Size

Dietary Details Gluten-Free

Ingredient List

Vegetables

01 1 medium butternut squash, peeled, seeded, and cut into 1-inch cubes
02 1 medium onion, diced
03 2 cloves garlic, minced
04 3 cups baby spinach
05 Fresh parsley, for garnish

Meats & Protein

01 1 pound Italian sausage, sweet or spicy, casing removed
02 1 cup cooked quinoa

Dairy

01 1 cup shredded mozzarella cheese
02 ½ cup grated Parmesan cheese

Pantry & Spices

01 2 tablespoons olive oil
02 1 teaspoon dried thyme
03 1 teaspoon dried sage
04 1 teaspoon paprika
05 Salt and pepper, to taste

Liquids

01 1 cup chicken or vegetable broth

Steps

Step 01

Preheat Oven and Prepare Baking Dish: Preheat oven to 375°F. Lightly grease a 9x13-inch baking dish with cooking spray or olive oil.

Step 02

Sauté Onions: In a large skillet, heat olive oil over medium heat. Add diced onion and cook until translucent, about 5 minutes.

Step 03

Add Garlic: Add minced garlic and cook for 1 minute until fragrant.

Step 04

Brown Italian Sausage: Increase heat slightly, add Italian sausage, and cook until browned and cooked through, breaking it apart with a wooden spoon for 7–10 minutes.

Step 05

Cook Butternut Squash with Spices: Add butternut squash to the skillet. Stir in dried thyme, dried sage, paprika, salt, and pepper. Cook for 5–7 minutes, stirring occasionally, until squash starts to soften.

Step 06

Add Spinach and Quinoa: Add baby spinach and cooked quinoa, stirring until spinach wilts.

Step 07

Add Broth and Simmer: Pour in chicken or vegetable broth and simmer for 3–4 minutes.

Step 08

Transfer to Baking Dish: Transfer mixture to prepared baking dish. Spread evenly and top with shredded mozzarella and grated Parmesan cheese.

Step 09

Bake Covered: Cover with aluminum foil and bake in preheated oven for 25 minutes.

Step 10

Bake Uncovered Until Golden: Remove foil and bake for an additional 15–20 minutes until cheese is bubbly and golden brown.

Step 11

Rest and Garnish: Remove from oven and let cool for 5 minutes. Garnish with fresh parsley before serving.

Equipment Needed

  • Large skillet
  • 9x13-inch baking dish
  • Chef's knife
  • Cutting board
  • Wooden spoon
  • Measuring cups and spoons
  • Aluminum foil

Allergy Info

Double-check every item for known allergies. If unsure, reach out to a healthcare provider.
  • Contains dairy (mozzarella, Parmesan). Contains potential gluten in sausage or broth—use certified gluten-free versions if needed. Contains possible sulfites in sausage. May contain celery in some broths.

Nutrition Details (each serving)

Nutrient details are offered for reference only. Speak with your doctor for personal health questions.
  • Calorie Count: 350
  • Fat Content: 19 g
  • Carbohydrate: 27 g
  • Proteins: 20 g